For most people, only the amount in box 1 (wages, tips, other compensation) needs to be reported as income on your tax return. If you are an employee who receives tips, you may have to include the amount from box 8 (allocated tips) as income on your return.
Any employer-provided dependent care benefits listed in box 10 that are not excludable from income must be reported as wages on Form 1040 (PDF) or Form 1040A (PDF). Any credit taken for child and dependent care expenses must be reported on your return. Refer to Form 2441 (PDF), or Form 1040A, Schedule 2 (PDF) Child and Dependent Care Expenses, to determine the amount, if any, of the exclusion or credit.
Employer-provided adoption benefits that must be used to complete Form 8839 (PDF), Qualified Adoption Expenses, appear in box 12 with a code T. Employer contributions to a medical savings account (MSA), which you report on Form 8853 (PDF), Archer MSAs and Long-Term Care Insurance Contracts, also appear in box 12 with a code R. Employer-provided benefits may be taxable as compensation under certain conditions. Refer to the relevant form instructions.
If you received advanced earned income credit payments from your employer (box 9), you must include the amount on your individual income tax return Form 1040 (PDF) or Form 1040A (PDF).
The other boxes either display information that the employer wanted to provide to you, or contain information that must be reported to the Social Security Administration or to the IRS.
References:
Source: www.irs.gov